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Thursday, April 23, 2009

Dialysis research


LONDON — Scientists have grown blood vessels for kidney patients from their own cells, making it easier and safer for them to use dialysis machines, according to a new study published today in the medical journal Lancet.

Some experts said the results suggested that doctors might one day be able to custom-produce blood vessels for patients with circulatory problems in their hearts or legs. Todd McAllister of Cytograft Tissue Engineering in California and colleagues implanted lab-grown blood vessels into 10 patients with advanced kidney disease in Argentina and Poland from 2004 to 2007.

Dialysis patients need a vessel, or shunt, to connect them to dialysis machines. This can be made from their own vessels. But because dialysis is done so regularly, kidney patients often run out of healthy vessels and need an artificial one .


McAllister said he and his team plan to test similar devices in patients with heart and leg problems.

Dr. Bryan Becker, president of the National Kidney Foundation in the U.S., said about half of kidney patients could benefit from these vessels if further tests confirm they work. Becker was not linked to the Lancet study.

by the associated press